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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf8f3b9ee3feadccd0e6e318252ce5a59283f36c5d00f3c9a817f66dde285c93' 
  AND token = 'MHauubIz/DmfoQs13UmqDCZ9+ZnDeeIrgKcvHO2shho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}