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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18d89e50cc87bea0c50440154e25b36f17a5a2027d9161f0e9a6c5f41ed425a7' 
  AND token = 'LEt6g4o9sf02S+L9zxDDVwDT1hR6tMW3tWHZAdtgUVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}