SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd8f0b9a8de369070c39aa6f548d1ea5442aecd8cbd5682f0fc88b5e12d2acac' 
  AND token = 'LKqYAhe+6xgK4vSEdvbdAdtLGmdenk3l7fyFEfDlvoQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}