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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33e7e81b2993642365e93d494c521a78897a9703e16ad1aa2dbb8aff0a396ff1' 
  AND token = 'hI4G13xanm6JF/2+uza2KGSE0LLe+CHSlDZOxbxBQ30=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}