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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4c18473d214d23e00732a0addb8c25a0d2127172d680af17279ec6454def210' 
  AND token = '+0CMio9HAYM/kt4gxI2QzSO7xasOOIiLp//6Bh67Nno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}