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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b725377bd762b324a05e40dcbb5c4111b0ec8946e5934b1744dc8039d519c84e' 
  AND token = 'zz/YMRoifVyKoEiwyYkFhdzgX5SmQsa8tjW2yP7dvSM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}