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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00e5d51a45d258f6e9e7c2d742b3917a72af923d5a494e585cb4eab4b80483cb' 
  AND token = 'OnIa2k3ZoTMZMpTJ0dLGIU6aa+aUL5QCcjMnBxlTQik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}