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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5180c983ffca0a0a777a803584ab4ac62244684f6ab2512f03025d2a4a97f8f4' 
  AND token = 'ECW2XEOxXpr5B3dmymsS4hpTR1uM2K6BkqxPIzDSKMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}