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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '406b10737a5271cfde4dcd36d25ee8cb995e13f7da3e81a0745d45425c73665f' 
  AND token = 'aZsNh9Cv9OthO9KbOMgqOnk+eBgtrb0NSwCsmF7p5SA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}