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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1489a3f81a34b05f46e78d52ad3c7e442dc424b0a0c1a2679e13edcc0906323a' 
  AND token = 'u+HZG1PPOJO3KEI3y0QfM6UfEsFxS+mLfRw+43e+BE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}