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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9726cdfce0b9a60a7c8d22eed44bbaf720db1e2fa67ad536e581e2140f1f724f' 
  AND token = 'CZqUrW1RjABH12XOazbO9BXUL37Wq7DcOA90Rjlrnzg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}