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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '412c0f232e5d6ce9698d0b4947660bcb9b36f08f891179c78b006a121246c468' 
  AND token = 'aEXQZ1mx8vB/xqcOCkp+OHNVpDhM2GP9lT268piy9N8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}