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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f114ad62987d71b9d237cc99636c1f405f7d1cd0c7b34947da70d18a258a704' 
  AND token = '1MePJhLq/XesQPumYSqHjax3r6930mmE47rj9/tmDVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}