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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '573e6a98885600ee373e843e18fe6bbfe627ea5cdb1093b5624f0c157ce74321' 
  AND token = 'WBx0rRIOrjWcuOLzk2uuFYzWkJlMzJyozp86uswtrg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}