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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33fc1298653353fcf028997cf487f3c1430a8bdeb5bb9ab4de0378ac4f2e1dcb' 
  AND token = 'GSOJ4dl0W+JfpW8VsDHWlNE9i8hryq+HBb6uNB6F1hE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}