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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd41cffaaad2f4b6aa16d3b8111dcd6ca110cd8148b9fd7d164f88f5ca4e9a65f' 
  AND token = '+/4Lu8jueDc+jwURP/KZ1IBUiRMh0V2tvUey9E5DQd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}