SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '321d2e6941f6bfcdccbb8b471d6f266b35b56b7ad9b283523574ec159dd4dbd6' 
  AND token = 'O8nnyLzRUGgplAkLlQR+IiTHreafUP3GO+BnPonxPTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}