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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41c2d47880a533e27413b5f4db64258a7588d6a01d12daea9c148d35f22634aa' 
  AND token = 'xIHNLXnPqEIEbh9dgGr8JJcbUwU9r/MGvlbPAu4mv4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}