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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1181a64238d257c44dd6fed00528db8cfcf1e723e935e8cd8cbcd857f857f1c4' 
  AND token = 'nW37QlGijjCrrqAUhWdSVei0l0aCvs/KihZ0Rm8XlqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}