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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '446980f709b9bd0ad7d0351fd5e92e175a290f5b9b39476f8445370473ed10ed' 
  AND token = 'LcsYIRVS8FMCNzxhWykcOb6gjM/IbdWu5iYIYg/FVHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}