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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acbe4596a729a3ababbbd2147059b66ab50393e8db77023651db103d607d91ed' 
  AND token = 'MrkuMvygayK4lMg+MGQgY64JjW4clHNXyZm6vHKgeKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}