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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '825e3d73badc2f725074db88c125d2d51415468c500e6f9d7606b03e2b94b6ac' 
  AND token = 'caRQPb5TcrqXmNlC+ASCoASEa1dQui6hjsB1hmYWB8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}