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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b268bc9d6e022ff89df02f84eed38204535201cc33a4f627dd1c942d316c2b4' 
  AND token = '2R5s7m4kdnDgIld8dTIjXWXWtV0+wdfqccUspNVM6Ls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}