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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '428f8c86d292586ec9dbdc2d09128de714993183889b8c15bf1a6c3cad0ce858' 
  AND token = '+kSVHOnZI0VdnOZWO7Q6kFjWTZeWxIxvZc/AY4I6vgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}