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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '722b283a36b11b5b85deb26f7485d6f0fb43ce43885363a3f98d35a196d54378' 
  AND token = 'Mk6Br45A/7qOFLazgImd3FqM29JjF7CObgT7fm/H/ww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}