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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f8742fc21c25a2f2aaa298dd7999a1262cef837d77fe1513bc9c49f79b81079' 
  AND token = 'ZD2hFldBKoK+7GGSPt6PWMWw50N2Hhyxa1VPyEKzzfI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}