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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e413be6987f3d23a050aa4e239796f6a75b657dbf8fe5b0670350646536de24' 
  AND token = 'TVX9tO9q1CkG+fgSR53XWA0gGzEVHear3ON36CLJUt8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}