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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9dd32ed2795184bb91619703182f8e997878d1b3265d28da583bfba7c7c96a2' 
  AND token = 'ARd92xyY1yRABLzlBlbKbACmGGV34AGYcSlNki4gNL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}