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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '538448cbca7b2d8a6d0eebd018d1c219fa3f71f454a76a226a9a68bc30f3e9c6' 
  AND token = 'XMoF/3XpVgp0X/1HMFew1ugqlVDfxBtT/BnEWJxRkNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}